CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | Parathion hydrolase |
Enzyme Information
| 3.1.8.1 |
Aryldialkylphosphatase.
based on mapping to UniProt P0A433
An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.
-!- Acts on organophosphorus compounds (such as paraoxon) including esters of phosphonic and phosphinic acids. -!- Inhibited by chelating agents. -!- Previously regarded as identical with EC 3.1.1.2.
|
UniProtKB Entries (1)
| P0A433 |
OPD_SPHSA
Sphingobium fuliginis
Parathion hydrolase
|
PDB Structure
| PDB | 1P6B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site.
J.Am.Chem.Soc.
|
