CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | S-(hydroxymethyl)glutathione dehydrogenase |
Enzyme Information
| 1.1.1.2 |
Alcohol dehydrogenase (NADP(+)).
based on mapping to UniProt O57380
An alcohol + NADP(+) = an aldehyde + NADPH.
-!- Some members of this group oxidize only primary alcohols; others act also on secondary alcohols. -!- May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55. -!- Re-specific with respect to NADPH.
|
UniProtKB Entries (1)
| O57380 |
ADH8_PELPE
Pelophylax perezi
NADP-dependent alcohol dehydrogenase
|
PDB Structure
| PDB | 1P0F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8)
J.Mol.Biol.
|
