CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1380 | Methylglyoxal synthase-like domain |
Domain Context
CATH Clusters
Superfamily | Methylglyoxal synthase-like domain |
Functional Family |
Enzyme Information
3.5.4.10 |
IMP cyclohydrolase.
based on mapping to UniProt P31335
IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
|
2.1.2.3 |
Phosphoribosylaminoimidazolecarboxamide formyltransferase.
based on mapping to UniProt P31335
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide.
|
UniProtKB Entries (1)
P31335 |
PUR9_CHICK
Gallus gallus
Bifunctional purine biosynthesis protein PURH
|
PDB Structure
PDB | 1OZ0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structure of Avian AICAR Transformylase with a Multisubstrate Adduct Inhibitor beta-DADF Identifies the Folate Binding Site.
Biochemistry
|