CATH Classification

Domain Context

CATH Clusters

Superfamily GHMP Kinase, N-terminal domain
Functional Family Ribonuclease PH

Enzyme Information

2.7.7.56
tRNA nucleotidyltransferase.
based on mapping to UniProt P28619
tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.
-!- Brings about the final exonucleolytic trimming of the 3'-terminus of tRNA precursors in Escherichia coli by a phosphorolysis, producing a mature 3'-terminus in tRNA and nucleoside diphosphate. -!- Not identical with EC 2.7.7.8.

UniProtKB Entries (1)

P28619
RNPH_BACSU
Bacillus subtilis subsp. subtilis str. 168
Ribonuclease PH

PDB Structure

PDB 1OYS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis and implications for its quaternary structure and tRNA binding.
Harlow, L.S., Kadziola, A., Jensen, K.F., Larsen, S.
Protein Sci.
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