CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1170 | Aldehyde Oxidoreductase; domain 3 |
|
3.90.1170.30 | Pyrimidine nucleoside phosphorylase-like, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Pyrimidine nucleoside phosphorylase-like, C-terminal domain |
| Functional Family | Thymidine phosphorylase |
Enzyme Information
| 2.4.2.4 |
Thymidine phosphorylase.
based on mapping to UniProt P07650
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.
|
UniProtKB Entries (1)
| P07650 |
TYPH_ECOLI
Escherichia coli K-12
Thymidine phosphorylase
|
PDB Structure
| PDB | 1OTP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol.
|
