CATH Classification

Domain Context

CATH Clusters

Superfamily Macrophage Migration Inhibitory Factor
Functional Family

Enzyme Information

5.3.3.10
5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
based on mapping to UniProt Q05354
5-carboxymethyl-2-hydroxymuconate = (3E,5R)-5-carboxy-2-oxohept-3- enedioate.
-!- Part of the homoprotocatechuate degradation pathway in Escherichia coli C.

UniProtKB Entries (1)

Q05354
HPCD_ECOLX
Escherichia coli
5-carboxymethyl-2-hydroxymuconate Delta-isomerase

PDB Structure

PDB 1OTG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases.
Subramanya, H.S., Roper, D.I., Dauter, Z., Dodson, E.J., Davies, G.J., Wilson, K.S., Wigley, D.B.
Biochemistry
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