CATH Domain 1oifA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.80	Glycosidases

Domain Context

CATH Clusters

Superfamily	Glycosidases
Functional Family	Beta-glucosidase 6-phospho-beta-glucosidase

Enzyme Information

3.2.1.21

Beta-glucosidase.

based on mapping to UniProt Q08638

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

-!- Wide specificity for beta-D-glucosides. -!- Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides.

UniProtKB Entries (1)

Q08638

BGLA_THEMA

Thermotoga maritima MSB8

Beta-glucosidase A

PDB Structure

PDB	1OIF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases Zechel, D.L., Boraston, A.B., Gloster, T., Boraston, C.M., Macdonald, J.M., Tilbrook, D.M., Stick, R.V., Davies, G.J. J.Am.Chem.Soc.