CATH Domain 1o4sA02

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	Aspartate aminotransferase

2.6.1.1

Aspartate transaminase.

based on mapping to UniProt Q9X0Y2

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

AAT_THEMA

Thermotoga maritima MSB8

Aspartate aminotransferase

PDB	1O4S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L.S., Canaves, J.M., Cambell, J., Chiu, H.J., Dai, X., Deacon, A.M., DiDonato, M., Elsliger, M.A., Eshagi, S., Floyd, R., Godzik, A., Grittini, C., Grzechnik, S.K., Hampton, E., Karlak, C., Klock, H.E., Koesema, E., Kovarik, J.S., Kreusch, A., Kuhn, P., Lesley, S.A., Levin, I., McMullan, D., McPhillips, T.M., Miller, M.D., Morse, A., Moy, K., Ouyang, J., Page, R., Quijano, K., Robb, A., Spraggon, G., Stevens, R.C., van den Bedem, H., Velasquez, J., Vincent, J., Wang, X., West, B., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Wilson, I.A. Proteins