CATH Domain 1o2kA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Cationic trypsin

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00760

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

TRY1_BOVIN

Bos taurus

Cationic trypsin

PDB Structure

PDB	1O2K
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors Katz, B.A., Elrod, K., Verner, E., Mackman, R.L., Luong, C., Shrader, W.D., Sendzik, M., Spencer, J.R., Sprengeler, P.A., Kolesnikov, A., Tai, V.W.-F., Hui, H.C., Breitenbucher, J.G., Allen, D., Janc, J.W. J.Mol.Biol.