CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.12 | Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 |
|
1.10.12.10 | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
| Functional Family |
Enzyme Information
| 3.8.1.7 |
4-chlorobenzoyl-CoA dehalogenase.
based on mapping to UniProt A5JTM5
4-chlorobenzoyl-CoA + H(2)O = 4-hydroxybenzoyl CoA + chloride.
-!- Specific for dehalogenation at the 4-position. -!- Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position. -!- This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
|
UniProtKB Entries (1)
| A5JTM5 |
CBADH_PSEUC
Pseudomonas sp. CBS3
4-chlorobenzoyl coenzyme A dehalogenase
|
PDB Structure
| PDB | 1NZY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of 4-chlorobenzoyl coenzyme A dehalogenase determined to 1.8 A resolution: an enzyme catalyst generated via adaptive mutation.
Biochemistry
|
