CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Tyrosine-protein kinase Fyn

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P06241
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P06241
FYN_HUMAN
Homo sapiens
Tyrosine-protein kinase Fyn

PDB Structure

PDB 1NYF
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure and peptide binding of the SH3 domain from human Fyn.
Morton, C.J., Pugh, D.J., Brown, E.L., Kahmann, J.D., Renzoni, D.A., Campbell, I.D.
Structure
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