CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.10 | DNA helicase RuvA subunit, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | DNA helicase RuvA subunit, C-terminal domain |
| Functional Family |
Enzyme Information
| 2.1.1.297 |
Peptide chain release factor N(5)-glutamine methyltransferase.
based on mapping to UniProt Q9WYV8
S-adenosyl-L-methionine + [peptide chain release factor 1 or 2]-L- glutamine = S-adenosyl-L-homocysteine + [peptide chain release factor 1 or 2]-N(5)-methyl-L-glutamine.
-!- Modifies the glutamine residue in the universally conserved glycylglycylglutamine (GGQ) motif of peptide chain release factor, resulting in almost complete loss of release activity. -!- Formerly EC 2.1.1.n16.
|
UniProtKB Entries (1)
| Q9WYV8 |
PRMC_THEMA
Thermotoga maritima MSB8
Release factor glutamine methyltransferase
|
PDB Structure
| PDB | 1NV8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structures along the Catalytic Pathway of PrmC/HemK, an N(5)-Glutamine
AdoMet-Dependent Methyltransferase
Biochemistry
|
