CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.50 | FAD/NAD(P)-binding domain |
|
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
| Superfamily | FAD/NAD(P)-binding domain |
| Functional Family | Glycine oxidase ThiO |
Enzyme Information
| 1.4.3.19 |
Glycine oxidase.
based on mapping to UniProt O31616
Glycine + H(2)O + O(2) = glyoxylate + NH(3) + H(2)O(2).
-!- The enzyme from Bacillus subtilis is active with glycine, sarcosine, N-ethylglycine, D-alanine, D-alpha-aminobutyrate, D-proline, D-pipecolate and N-methyl-D-alanine. -!- It differs from EC 1.4.3.3 due to its activity on sarcosine and D-pipecolate. -!- The intermediate 2-iminoacetate is used directly by EC 2.8.1.10.
|
UniProtKB Entries (1)
| O31616 |
GLYOX_BACSU
Bacillus subtilis subsp. subtilis str. 168
Glycine oxidase
|
PDB Structure
| PDB | 1NG3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis
Biochemistry
|
