CATH Domain 1n46A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Thyroid hormone receptor beta 2

Enzyme Information

UniProtKB Entries (1)

THB_HUMAN

Homo sapiens

Thyroid hormone receptor beta

PDB Structure

PDB	1N46
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Discovery of a Novel Series of 6-Azauracil-Based Thyroid Hormone Receptor Ligands: Potent, TRbeta Subtype-Selective Thyromimetics Dow, R.L., Schneider, S.R., Paight, E.S., Hank, R.F., Chiang, P., Cornelius, P., Lee, E., Newsome, W.P., Swick, A.G., Spitzer, J., Hargrove, D.M., Patterson, T.A., Pandit, J., Chrunyk, B.A., LeMotte, P.K., Danley, D.E., Rosner, M.H., Ammirati, M.J., Simons, S.P., Schulte, G.K., Tate, B.F., DaSilva-Jardine, P. Bioorg.Med.Chem.Lett.