CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.100 |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.100 |
| Functional Family | Zinc/cadmium/lead-transporting P-type ATPase |
Enzyme Information
| 7.2.2.12 |
P-type Zn(2+) transporter.
based on mapping to UniProt P37617
ATP + H(2)O + Zn(2+)(Side 1) = ADP + phosphate + Zn(2+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn(2+) and the related cations Cd(2+) and Pb(2+). -!- Formerly EC 3.6.3.5.
|
| 3.6.3.3 |
Cadmium-exporting ATPase.
based on mapping to UniProt P37617
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
|
| 7.2.2.- |
Linked to the hydrolysis of a nucleoside triphosphate.
based on mapping to UniProt P37617
|
UniProtKB Entries (1)
| P37617 |
ZNTA_ECOLI
Escherichia coli K-12
Zinc/cadmium/lead-transporting P-type ATPase
|
PDB Structure
| PDB | 1MWY |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
A new zinc-protein coordination site in intracellular metal trafficking: solution structure of the apo and Zn(II) forms of ZntA (46-118)
J.Mol.Biol.
|
