1 keywords

CATH Domain 1mjgN05

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.1470 Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase(codh/acs), Chain M, domain 5
Homologous Superfamily 3.40.1470.10 Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase(codh/acs), Chain M, domain 5

Domain Context

CATH Clusters

Superfamily Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase(codh/acs), Chain M, domain 5
Functional Family

Enzyme Information

2.3.1.169
CO-methylating acetyl-CoA synthase.
based on mapping to UniProt P27988
Acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl- Co(III) corrinoid Fe-S protein].
-!- Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO(2) and H(2).

UniProtKB Entries (1)

P27989
DCMB_MOOTH
Moorella thermoacetica
Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit beta

PDB Structure

PDB 1MJG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase
Doukov, T.I., Iverson, T.M., Seravalli, J., Ragsdale, S.W., Drennan, C.L.
Science