CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonucleotide Reductase, subunit A
Functional Family

Enzyme Information

1.14.13.25
Methane monooxygenase (soluble).
based on mapping to UniProt P27354
Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O.
-!- The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3. -!- Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO(2), ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.

UniProtKB Entries (1)

P27355
MEMG_METTR
Methylosinus trichosporium
Methane monooxygenase component A gamma chain

PDB Structure

PDB 1MHZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b
Elango, N., Radhakrishnan, R., Froland, W.A., Wallar, B.J., Earhart, C.A., Lipscomb, J.D., Ohlendorf, D.H.
Protein Sci.