CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Protein disulfide-isomerase

Enzyme Information

5.3.4.1
Protein disulfide-isomerase.
based on mapping to UniProt P07237
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.

UniProtKB Entries (1)

P07237
PDIA1_HUMAN
Homo sapiens
Protein disulfide-isomerase

PDB Structure

PDB 1MEK
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structure determination of the N-terminal thioredoxin-like domain of protein disulfide isomerase using multidimensional heteronuclear 13C/15N NMR spectroscopy.
Kemmink, J., Darby, N.J., Dijkstra, K., Nilges, M., Creighton, T.E.
Biochemistry