CATH Domain 1mbbA01

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.78	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1
	3.90.78.10	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

Superfamily	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family	UDP-N-acetylenolpyruvoylglucosamine reductase

1.3.1.98

UDP-N-acetylmuramate dehydrogenase.

based on mapping to UniProt P08373

UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.

-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

MURB_ECOLI

Escherichia coli K-12

UDP-N-acetylenolpyruvoylglucosamine reductase

PDB	1MBB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Lees, W.J., Benson, T.E., Hogle, J.M., Walsh, C.T. Biochemistry