CATH Domain 1m8oB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.5	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	1.20.5.630	Integrin beta subunit, cytoplasmic domain

Domain Context

CATH Clusters

Superfamily	Integrin beta subunit, cytoplasmic domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

ITA2B_HUMAN

Homo sapiens

Integrin alpha-IIb

PDB Structure

PDB	1M8O
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	A Structural mechanism of integrin alfaiib beta3 "Inside-out" Activation as regulated by its cytoplasmic face. Vinogradova, O., Velyvis, A., Velyviene, A., Hu, B., Haas, T.A., Plow, E.F., Qin, J. Cell(Cambridge,Mass.)