CATH Domain 1m83A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.240	Tyrosyl-Transfer RNA Synthetase
	1.10.240.10	Tyrosyl-Transfer RNA Synthetase

Domain Context

CATH Clusters

Superfamily	Tyrosyl-Transfer RNA Synthetase
Functional Family	Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2

Tryptophan--tRNA ligase.

based on mapping to UniProt P00953

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

SYW_GEOSE

Geobacillus stearothermophilus

Tryptophan--tRNA ligase

PDB Structure

PDB	1M83
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations. Retailleau, P., Huang, X., Yin, Y., Hu, M., Weinreb, V., Vachette, P., Vonrhein, C., Bricogne, G., Roversi, P., Ilyin, V., Carter, C.W. J.Mol.Biol.