CATH Classification

Domain Context

CATH Clusters

Superfamily Ricin (A Subunit), domain 2
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P81446
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P81446
ML1_VISAL
Viscum album
Beta-galactoside-specific lectin 1

PDB Structure

PDB 1M2T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallisation under microgravity of mistletoe lectin I from Viscum album with adenine monophosphate and the crystal structure at 1.9 A resolution.
Krauspenhaar, R., Rypniewski, W., Kalkura, N., Moore, K., DeLucas, L., Stoeva, S., Mikhailov, A., Voelter, W., Betzel, C.h.
Acta Crystallogr.,Sect.D
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