CATH Domain 1lm6A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.45	Peptide Deformylase
	3.90.45.10	Peptide deformylase

Domain Context

CATH Clusters

Superfamily	Peptide deformylase
Functional Family	Peptide deformylase

Enzyme Information

3.5.1.88

Peptide deformylase.

based on mapping to UniProt Q9F2F0

Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide.

-!- Requires at least a dipeptide for an efficient rate of reaction. -!- N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. -!- Differs in substrate specificity from EC 3.5.1.27 and EC 3.5.1.31.

UniProtKB Entries (1)

Q9F2F0

DEF_STRPN

Streptococcus pneumoniae TIGR4

Peptide deformylase

PDB Structure

PDB	1LM6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase Kreusch, A., Spraggon, G., Lee, C.C., Klock, H., McMullan, D., Ng, K., Shin, T., Vincent, J., Warner, I., Ericson, C., Lesley, S.A. J.MOL.BIOL.