CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family | Malate dehydrogenase |
Enzyme Information
1.1.1.27 |
L-lactate dehydrogenase.
based on mapping to UniProt P00343
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.
|
UniProtKB Entries (1)
P00343 |
LDH_LACCA
Lactobacillus casei
L-lactate dehydrogenase
|
PDB Structure
PDB | 1LLC |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS-CASEI AT 3A RESOLUTION.
Acta Crystallogr.,Sect.A
|