CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Protein-glutamine gamma-glutamyltransferase 2 |
Enzyme Information
| 2.3.2.13 |
Protein-glutamine gamma-glutamyltransferase.
based on mapping to UniProt Q08188
A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)- (gamma-glutamyl)-L-lysine cross-link + NH(3).
-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine cross-links.
|
UniProtKB Entries (1)
| Q08188 |
TGM3_HUMAN
Homo sapiens
Protein-glutamine gamma-glutamyltransferase E
|
PDB Structure
| PDB | 1L9N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Spodoptera |
| Primary Citation |
Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation.
EMBO J.
|
