CATH Classification
Domain Context
CATH Clusters
| Superfamily | 1.10.1610.10 |
| Functional Family | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase |
Enzyme Information
| 2.4.2.21 |
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase.
based on mapping to UniProt Q05603
Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5'-phosphate.
-!- Also acts on benzimidazole, and the clostridial enzyme acts on adenine to form 7-alpha-D-ribosyladenine 5'-phosphate. -!- The product of the reaction, alpha-ribazole 5'-phosphate, forms part of the corrin biosynthesis pathway and is a substrate for EC 2.7.8.2. -!- It can also be dephosphorylated to form alpha-ribazole by the action of EC 3.1.3.73.
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UniProtKB Entries (1)
| Q05603 |
COBT_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
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PDB Structure
| PDB | 1L5K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Salmonella |
| Primary Citation |
Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry
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