CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Guanine nucleotide exchange factor DBS

Enzyme Information

UniProtKB Entries (2)

Q64096
MCF2L_MOUSE
Mus musculus
Guanine nucleotide exchange factor DBS
P60953
CDC42_HUMAN
Homo sapiens
Cell division control protein 42 homolog

PDB Structure

PDB 1KZ7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
Rossman, K.L., Worthylake, D.K., Snyder, J.T., Siderovski, D.P., Campbell, S.L., Sondek, J.
EMBO J.
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