CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.230 | Ribosomal Protein S5; domain 2 |
|
3.30.230.10 |
Domain Context
CATH Clusters
| Superfamily | 3.30.230.10 |
| Functional Family | Mevalonate kinase |
Enzyme Information
| 2.7.1.36 |
Mevalonate kinase.
based on mapping to UniProt P17256
ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate.
-!- CTP, GTP and UTP can also act as donors.
|
UniProtKB Entries (1)
| P17256 |
KIME_RAT
Rattus norvegicus
Mevalonate kinase
|
PDB Structure
| PDB | 1KVK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The Structure of a Binary complex
between a Mammalian Mevalonate Kinase and ATP: Insights into the
Reaction Mechanism and Human Inherited Disease
J.Biol.Chem.
|
