CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.2350 | Pseudouridine synthase | |
3.30.2350.10 | Pseudouridine synthase |
Domain Context
CATH Clusters
Superfamily | Pseudouridine synthase |
Functional Family |
Enzyme Information
5.4.99.19 |
16S rRNA pseudouridine(516) synthase.
based on mapping to UniProt P0AA43
16S rRNA uridine(516) = 16S rRNA pseudouridine(516).
-!- The enzyme is specific for uridine(516) in 16S rRNA. -!- In vitro, the enzyme does not modify free 16S rRNA. -!- The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.
|
UniProtKB Entries (1)
P0AA43 |
RSUA_ECOLI
Escherichia coli K-12
Ribosomal small subunit pseudouridine synthase A
|
PDB Structure
PDB | 1KSL |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol.
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