CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.10 | Seminal Fluid Protein PDC-109 (Domain B) |
|
2.10.10.10 | Fibronectin, type II, collagen-binding |
Domain Context
CATH Clusters
| Superfamily | Fibronectin, type II, collagen-binding |
| Functional Family | 72 kDa type IV collagenase |
Enzyme Information
| 3.4.24.24 |
Gelatinase A.
based on mapping to UniProt P08253
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
-!- Belongs to peptidase family M10B.
|
UniProtKB Entries (1)
| P08253 |
MMP2_HUMAN
Homo sapiens
72 kDa type IV collagenase
|
PDB Structure
| PDB | 1KS0 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
The col-1 module of human matrix metalloproteinase-2 (MMP-2): structural/functional relatedness between gelatin-binding fibronectin type II modules and lysine-binding kringle domains.
Biol.Chem.
|
