CATH Classification

Domain Context

CATH Clusters

Superfamily Plasminogen Kringle 4
Functional Family Plasminogen

Enzyme Information

3.4.21.7
Plasmin.
based on mapping to UniProt P00747
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
-!- Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.14.

UniProtKB Entries (1)

P00747
PLMN_HUMAN
Homo sapiens
Plasminogen

PDB Structure

PDB 1KRN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human plasminogen kringle 4 at 1.68 a and 277 K. A possible structural role of disordered residues.
Stec, B., Yamano, A., Whitlow, M., Teeter, M.M.
Acta Crystallogr.,Sect.D