CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.25 | Alpha Horseshoe |
|
1.25.40 | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
|
1.25.40.10 | Tetratricopeptide repeat domain |
Domain Context
CATH Clusters
| Superfamily | Tetratricopeptide repeat domain |
| Functional Family | Beta-lactamase HcpB |
Enzyme Information
| 3.5.2.6 |
Beta-lactamase.
based on mapping to UniProt O25103
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.
|
UniProtKB Entries (1)
| O25103 |
HCPB_HELPY
Helicobacter pylori 26695
Beta-lactamase HcpB
|
PDB Structure
| PDB | 1KLX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein.
J.Biol.Chem.
|
