CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.60 | Lipoxygenase-1 |
|
2.60.60.20 | PLAT/LH2 domain |
Domain Context
CATH Clusters
| Superfamily | PLAT/LH2 domain |
| Functional Family |
Enzyme Information
| 3.1.4.3 |
Phospholipase C.
based on mapping to UniProt Q9RF12
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.
|
UniProtKB Entries (1)
| Q9RF12 |
PHLC_CLOPF
Clostridium perfringens
Phospholipase C
|
PDB Structure
| PDB | 1KHO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
Biochemistry
|
