CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.720 | Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 |
|
1.10.720.50 | PWWP, helical domain |
Domain Context
CATH Clusters
| Superfamily | PWWP, helical domain |
| Functional Family | DNA (Cytosine-5)-methyltransferase 3B isoform X2 |
Enzyme Information
| 2.1.1.37 |
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt O88509
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.
|
UniProtKB Entries (1)
| O88509 |
DNM3B_MOUSE
Mus musculus
DNA (cytosine-5)-methyltransferase 3B
|
PDB Structure
| PDB | 1KHC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nat.Struct.Biol.
|
