CATH Classification

Domain Context

CATH Clusters

Superfamily Argininosuccinate synthetase, chain A, domain 2
Functional Family Argininosuccinate synthase

Enzyme Information

6.3.4.5
Argininosuccinate synthase.
based on mapping to UniProt P59846
ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)- (L-arginino)succinate.

UniProtKB Entries (1)

P59846
ASSY_THET8
Thermus thermophilus HB8
Argininosuccinate synthase

PDB Structure

PDB 1KH3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of Argininosuccinate Synthetase in Enzyme-ATP Substrates and Enzyme-AMP Product Forms: STEREOCHEMISTRY OF THE CATALYTIC REACTION
Goto, M., Omi, R., Miyahara, I., Sugahara, M., Hirotsu, k.
J.Biol.Chem.