CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.238 | Recoverin; domain 1 |
|
1.10.238.10 | EF-hand |
Domain Context
CATH Clusters
| Superfamily | EF-hand |
| Functional Family | Calpain small subunit 1 |
Enzyme Information
UniProtKB Entries (1)
| P17655 |
CAN2_HUMAN
Homo sapiens
Calpain-2 catalytic subunit
|
PDB Structure
| PDB | 1KFX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Spodoptera |
| Primary Citation |
The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA
|
