CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Phospho-2-dehydro-3-deoxyheptonate aldolase |
Enzyme Information
| 2.5.1.54 |
3-deoxy-7-phosphoheptulonate synthase.
based on mapping to UniProt P0AB91
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D- arabino-hept-2-ulosonate 7-phosphate + phosphate.
-!- Formerly EC 4.1.2.15.
|
UniProtKB Entries (1)
| P0AB91 |
AROG_ECOLI
Escherichia coli K-12
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive
|
PDB Structure
| PDB | 1KFL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Allosteric inhibition of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase alters the coordination of both substrates.
J.Mol.Biol.
|
