CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.410 | Cholesterol Oxidase; domain 2 | |
3.30.410.10 | Cholesterol Oxidase; domain 2 |
Domain Context
CATH Clusters
Superfamily | Cholesterol Oxidase; domain 2 |
Functional Family |
Enzyme Information
1.1.99.18 |
Cellobiose dehydrogenase (acceptor).
based on mapping to UniProt Q01738
Cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.
-!- Also acts, more slowly, on cello-oligosaccharides, lactose and D-glucosyl-1,4-beta-D-mannose. -!- The enzyme from the white rot fungus Phanerochaete chrysosporium is unusual in having two redoxin domains, one containing a flavin and the other a protoheme group. -!- It transfers reducing equivalents from cellobiose to two types of redox acceptor: two-electron oxidants, including redox dyes, benzoquinones, and molecular oxygen, and one-electron oxidants, including semiquinone species, iron(II) complexes, and the model acceptor cytochrome c. -!- 2,6-dichloroindophenol can act as acceptor in vitro.
|
UniProtKB Entries (1)
Q01738 |
CDH_PHACH
Phanerochaete chrysosporium
Cellobiose dehydrogenase
|
PDB Structure
PDB | 1KDG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structure of the Flavoprotein Domain of the Extracellular Flavocytochrome Cellobiose Dehydrogenase
J.Mol.Biol.
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