CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.30 | Glutaredoxin | |
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
Superfamily | Glutaredoxin |
Functional Family |
Enzyme Information
1.8.4.- |
With a disulfide as acceptor.
based on mapping to UniProt P23202
|
1.11.1.9 |
Glutathione peroxidase.
based on mapping to UniProt P23202
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
|
UniProtKB Entries (1)
P23202 |
URE2_YEAST
Saccharomyces cerevisiae S288C
Transcriptional regulator URE2
|
PDB Structure
PDB | 1K0C |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.
Biochemistry
|