CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | Ribonuclease H |
Enzyme Information
| 3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt P0A7Y4
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
UniProtKB Entries (1)
| P0A7Y4 |
RNH_ECOLI
Escherichia coli K-12
Ribonuclease HI
|
PDB Structure
| PDB | 1JXB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.
Protein Sci.
|