CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Chromosome 19 SCAF14664, whole genome shotgun sequence |
Enzyme Information
| 1.1.1.205 |
IMP dehydrogenase.
based on mapping to UniProt P12269
Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.
-!- The enzyme acts on the hydroxy group of the hydrated derivative of the substrate. -!- Formerly EC 1.2.1.14.
|
UniProtKB Entries (1)
| P12269 |
IMDH2_CRIGR
Cricetulus griseus
Inosine-5'-monophosphate dehydrogenase 2
|
PDB Structure
| PDB | 1JR1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.
Cell(Cambridge,Mass.)
|
