CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.272.10
Functional Family DNA polymerase III, delta subunit

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P28630
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P0A988
DPO3B_ECOLI
Escherichia coli K-12
Beta sliding clamp

PDB Structure

PDB 1JQJ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Jeruzalmi, D., Yurieva, O., Zhao, Y., Young, M., Stewart, J., Hingorani, M., O'Donnell, M., Kuriyan, J.
Cell(Cambridge,Mass.)
CATH-Gene3D is a Global Biodata Core Resource Learn more...