CATH Domain 1jpyA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.90	Cystine Knot Cytokines, subunit B
	2.10.90.10	Cystine-knot cytokines

Domain Context

CATH Clusters

Superfamily	Cystine-knot cytokines
Functional Family	Interleukin-17A

Enzyme Information

UniProtKB Entries (1)

IL17F_HUMAN

Homo sapiens

Interleukin-17F

PDB Structure

PDB	1JPY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. Hymowitz, S.G., Filvaroff, E.H., Yin, J.P., Lee, J., Cai, L., Risser, P., Maruoka, M., Mao, W., Foster, J., Kelley, R.F., Pan, G., Gurney, A.L., de Vos, A.M., Starovasnik, M.A. EMBO J.