CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha-1-antitrypsin, domain 1
Functional Family Serpin family D member 1

Enzyme Information

UniProtKB Entries (1)

P00734
THRB_HUMAN
Homo sapiens
Prothrombin

PDB Structure

PDB 1JMO
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
Baglin, T.P., Carrell, R.W., Church, F.C., Esmon, C.T., Huntington, J.A.
Proc.Natl.Acad.Sci.USA
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