CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Chymotrypsin-like elastase family member 1

Enzyme Information

3.4.21.36
Pancreatic elastase.
based on mapping to UniProt P00772
Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.
-!- Formed by activation of proelastase from mammalian pancreas by trypsin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.

UniProtKB Entries (1)

P00772
CELA1_PIG
Sus scrofa
Chymotrypsin-like elastase family member 1

PDB Structure

PDB 1JIM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Stereospecific Reaction of 3-Methoxy-4-Chloro-7-Aminoisocoumarin with Crystalline Porcine Pancreatic Elastase
Meyer Junior, E.F., Presta, L.G., Radhakrishnan, R.
J.Am.Chem.Soc.
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