CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.50.10
Functional Family

Enzyme Information

3.2.1.14
Chitinase.
based on mapping to UniProt P20533
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta- linkages in chitin and chitodextrins.
-!- The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act. -!- Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase. -!- Cf. EC 3.2.1.202.

UniProtKB Entries (1)

P20533
CHIA1_BACCI
Bacillus circulans
Chitinase A1

PDB Structure

PDB 1ITX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Three-dimensional structure of the catalytic domain of chitinase A1 from Bacillus circulans WL-12 at a very high resolution
Matsumoto, T., Nonaka, T., Hashimoto, M., Watanabe, T., Mitsui, Y.
PROC.JPN.ACAD.,SER.B
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