CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3
Functional Family

Enzyme Information

4.1.99.3
Deoxyribodipyrimidine photo-lyase.
based on mapping to UniProt P61497
Cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).
-!- A flavoprotein containing a second chromophore group. -!- Catalyzes the reactivation by light of irradiated DNA. -!- A similar reactivation of irradiated RNA is probably due to a separate enzyme.

UniProtKB Entries (1)

P61497
PHR_THET8
Thermus thermophilus HB8
Deoxyribodipyrimidine photo-lyase

PDB Structure

PDB 1IQU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of thermostable DNA photolyase: pyrimidine-dimer recognition mechanism.
Komori, H., Masui, R., Kuramitsu, S., Yokoyama, S., Shibata, T., Inoue, Y., Miki, K.
Proc.Natl.Acad.Sci.USA