CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt Q5SIY4
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

Q5SIY4
LEU3_THET8
Thermus thermophilus HB8
3-isopropylmalate dehydrogenase

PDB Structure

PDB 1IPD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Three-dimensional structure of a highly thermostable enzyme, 3-isopropylmalate dehydrogenase of Thermus thermophilus at 2.2 A resolution.
Imada, K., Sato, M., Tanaka, N., Katsube, Y., Matsuura, Y., Oshima, T.
J.Mol.Biol.