CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.16 | Serine Protease, Human Cytomegalovirus Protease; Chain A |
|
3.20.16.10 | Herpesvirus/Caudovirus protease domain |
Domain Context
CATH Clusters
| Superfamily | Herpesvirus/Caudovirus protease domain |
| Functional Family | Capsid scaffolding protein |
Enzyme Information
| 3.4.21.97 |
Assemblin.
based on mapping to UniProt P16753
Cleaves -Ala-|-Ser- and -Ala-|-Ala- bonds in the scaffold protein.
-!- Involved in the breakdown of the scaffold protein during the late stages of assembly of the herpes-virus virion. -!- Inhibited by diisopropyl fluorophosphate. -!- Belongs to peptidase family S21.
|
UniProtKB Entries (1)
| P16753 |
SCAF_HCMVA
Human herpesvirus 5 strain AD169
Capsid scaffolding protein
|
PDB Structure
| PDB | 1IEG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
Biochemistry
|
