CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.160 | 3 Solenoid |
|
2.160.20 | Pectate Lyase C-like |
|
2.160.20.10 | Single-stranded right-handed beta-helix, Pectin lyase-like |
Domain Context
CATH Clusters
| Superfamily | Single-stranded right-handed beta-helix, Pectin lyase-like |
| Functional Family | Pectin lyase F |
Enzyme Information
| 4.2.2.10 |
Pectin lyase.
based on mapping to UniProt Q01172
Eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.
-!- Favors pectin, the methyl ester, over pectate, the anion (which is the preferred substrate of EC 4.2.2.2).
|
UniProtKB Entries (1)
| Q01172 |
PELA_ASPNG
Aspergillus niger
Pectin lyase A
|
PDB Structure
| PDB | 1IDJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases.
Structure
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